SANTA CLARA, CA--(Marketwire - January 8, 2008) - Symyx Technologies, Inc. (NASDAQ: SMMX) today announced plans to provide a live webcast of its presentation at the 26th Annual JPMorgan Healthcare Conference. The presentation, which is scheduled to begin at 10:30 a.m. PT on Thursday, January 10, will include an overview of the company, its business segments and products, strategy for growth, 2008 financial outlook and other matters relating to its business. The webcast audio and slides will be available in the Investors section of the company's web site at www.symyx.com for a period of two weeks.

About Symyx

Symyx Technologies, Inc. is the R&D execution partner to the life sciences, chemicals, energy, consumer products and electronics industries. Symyx provides electronic lab notebook and scientific decision-support software, automated lab systems (workflows) and collaborative research services to improve R&D productivity. In October 2007, Symyx acquired MDL Information Systems, Inc., a leading provider of innovative informatics software, databases and services that accelerate successful scientific R&D by improving the speed and quality of scientists' decision making. Information about Symyx, including reports and other information filed by Symyx with the Securities and Exchange Commission, is available at www.symyx.com.

Symyx is a registered trademark of Symyx Technologies, Inc. All rights reserved. All other trademarks mentioned in this document are the property of their respective owners.